精神障碍患者和没有精神障碍患者的功能比较:系统性审查和元分析
Yen-Jung Chen1, Chia-Chao Liu2, Chi-Chin Sun3
1Department of Psychiatry, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.
Biomedical journal
|February 27, 2026
概括
患有精神障碍的患者表现出较差的眼功能,由较低的眼破裂时间 (TBUT) 和希尔默测试结果表明. 这凸显了这一群体需要定期进行眼科护理监测的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 在患有精神疾病的患者中,眼睛护理往往被忽视.
- 现有关于精神障碍和干眼疾病的研究显示了不一致的客观眼功能数据.
- 这一元分析调查了精神障碍或没有精神障碍的个体的眼功能差异.
研究的目的:
- 系统地比较有精神障碍和没有精神障碍的患者之间的客观功能测量.
- 综合关于眼破裂时间 (TBUT) 和与心理健康状况相关的希尔默测试结果的证据.
- 识别心理健康状况和眼睛表面健康之间的潜在关联.
主要方法:
- 在Embase,PubMed,Cochrane和PsycINFO数据库中进行系统的文献搜索.
- 包括15项研究,包括3319名参与者,比较精神障碍和没有精神障碍的成年人眼功能 (Schirmer测试,TBUT).
- 使用随机效应模型来确定聚合平均差异的元分析.
主要成果:
- 患有精神障碍的患者表现出明显较低的撕裂破裂时间 (TBUT) (MD: -3.72) 和希尔默测试结果 (MD: -4.62).
- 这些发现在各种子组中是一致的,包括性别,国家,精神病诊断和药物使用.
- 即使在不服用精神病药物的患者中,也明显出现了降低的希尔默测试结果,这表明除了治疗效果之外还有直接联系.
结论:
- 与没有精神障碍的人相比,患有精神障碍的人表现出功能受损.
- 对于患有精神障碍的患者,建议对眼功能障碍进行例行监测.
- 由于研究异质性和横截面设计,研究结果应谨慎解释,作为假设生成.
更多相关视频
05:32Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
Published on: December 7, 2018
9.8K
09:55Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
13.3K
相关概念视频
Diagnostic and Statistical Manual of Mental Disorders (DSM)
1.4K
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
1.4K
Depressive Disorders: Etiology
793
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
793
Depressive Disorders: MDD and Dysthymia
918
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
918
