影响参与中风恢复研究的因素,重点关注多样性考虑:一项随机调查研究
Susan Marzolini1, Shannon L MacDonald2, Amy Y X Yu3
1KITE Research Institute; Toronto Rehabilitation Institute/University Health Network, Toronto, Ontario, Canada; Rehabilitation Sciences Institute, University of Toronto, Toronto, Canada.
概括
大多数中风幸存者同意与研究人员联系并同意试验. 种族化个体不太可能同意初始联系,突出了包容性招聘策略的必要性.
科学领域:
- 神经学 神经学
- 临床试验 临床试验
- 医疗保健服务研究 医疗服务研究
背景情况:
- 了解患者招募障碍对于有效的临床试验设计至关重要.
- 性别和种族/种族可以影响参与医学研究.
研究的目的:
- 调查性别和种族/种族如何影响同意与研究人员联系以及同意进行假设性中风试验.
主要方法:
- 卒中后的成年人完成了关于假设试验同意 (药物与安慰剂) 的调查.
- 评估研究人员联系和试验同意的动机,担忧和决策.
- 收集的人口,临床和心理社会数据.
主要成果:
- 对研究人员联系的高度同意 (89.2-96.9%) 和同意.
- 种族化个体不太可能同意与研究人员的初始联系 (p=0.02).
- 药物与安慰剂试验的同意率较低 (44.1%与>73%).
结论:
- 对中风试验参与的高度同意,在初始接触中存在子组差异.
- 建立信任和对文化敏感的招聘至关重要.
- 解决包容性研究的子组特定风险和好处.
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