肺粘膜菌:根据治疗方式和潜在的并发症情况的结果
Chelsea Powell1, Carlos A Puig2, Sahar A Saddoughi2
1Department of Surgery, Mayo Clinic, Rochester, MN; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
The Annals of thoracic surgery
|February 27, 2026
概括
手术切除改善了肺粘膜病患者的生存率. 然而,潜在的血液性恶性瘤与尽管接受治疗,但长期结果不佳有关.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 手术瘤学手术瘤学
背景情况:
- 肺粘膜菌是一种罕见的,严重的机会性真菌感染.
- 它主要影响具有并发症的免疫功能低下个体.
研究的目的:
- 确定影响外科手术选择的因素.
- 确定医院死亡率和整体存活率 (OS) 的预测因素.
主要方法:
- 一个中心对86名肺粘膜瘤患者 (2000-2021) 的综述.
- 排放状态的后勤回归;对OS进行日志等级测试.
- 分析手术干预,死亡率和生存数据.
主要成果:
- 医院死亡率为46.5%. 在医院死亡率为46.5%.
- 手术切除与抗真菌药物相结合,改善了出院后的生存率 (73.2%vs35.6%).
- 与实体器官移植接受者相比,血液恶性瘤与较低的骨系统相关.
结论:
- 手术切除可提高精选的肺粘膜病患者的存活率.
- 考虑进行手术,即使是双边或肺外疾病.
- 血液性恶性瘤预示着长期生存率不佳.
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