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Updated: Mar 1, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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双向门德尔随机化分析血液细胞表型,遗传变异和系统性红斑狼之间的关系

Ju Wei1, Hu Liang2

  • 1Emergency Department, Liuzhou Municipal Liutie Central Hospital, Liuzhou, Guangxi, China.

Medicine
|February 27, 2026
PubMed
概括

这项研究揭示了免疫细胞功能和系统性红斑狼 (SLE) 之间的双向遗传联系. 特定的免疫细胞反应影响了SLE风险,而SLE遗传因素改变了免疫细胞的行为,表明了新的治疗点.

关键词:
门德尔的随机化血细胞表型 血细胞表型因果关系是因果关系.遗传变异是一种遗传变异.系统性红血性狼 (Systemic Lupus Erythematosus) 是一种全身性狼.

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