吸烟和酒精消费是结肠异症及其并发症的危险因素:系统性审查和元分析
Eesha Chitneni1, Sawai Singh Rathore2, Nanush Damarlapally3
1Internal Medicine, Mediciti Institute of Medical Sciences, Hyderabad, India.
Medicine
|February 27, 2026
概括
吸烟和饮酒与更高的结肠分泌瘤 (CD) 风险有关. 这一元分析证实,吸烟增加了CD和出血风险,而酒精显示了与CD的潜在联系. 需要进一步的研究.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 结肠异 (CD) 是常见的,特别是在老年人中.
- 对CD的风险因素已被广泛研究,但吸烟和酒精的作用仍在争论中.
- 这一元分析调查了生活方式因素 (吸烟,酒精) 与CD风险和并发症之间的关联.
研究的目的:
- 分析吸烟,酒精消费和结肠异症 (CD) 风险之间的关系.
- 评估这些生活方式因素与CD的并发症,包括分泌体炎和分泌体出血之间的关联.
主要方法:
- 在PubMed,Embase和谷歌学者中进行了全面的文献搜索.
- 包括报告吸烟,饮酒和CD的观察性研究.
- 随机效应模型用于计算几率比率 (OR) 和95%置信区间 (CI);使用埃格尔和贝格-马祖马达测试来评估出版偏差.
主要成果:
- 分析了62项涉及566,903名参与者的研究.
- 吸烟显著增加了CD的风险 (OR:1.36),分泌体炎 (OR:1.59) 和分泌体出血 (OR:1.51).
- 酒精消费与CD风险增加有关 (OR:1.41),但不涉及分泌体出血或分泌体炎.
结论:
- 这一元分析表明,吸烟和饮酒与结肠异症的风险增加有关.
- 吸烟是CD及其并发症分支出血的重要危险因素.
- 酒精消费与节疾病之间的联系需要进一步研究潜在机制.
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