复星补充剂及其在与肥胖相关的非传染性疾病中的潜在益处
Chun-Yu Shen1, Chen-Pi Li2, Jui-Ting Yu1
1Division of Hematology/Medical Oncology, Department of Medicine, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan, R.O.C.
In vivo (Athens, Greece)
|February 27, 2026
概括
复星补充剂对肥胖中的代谢和炎症标志物提供了适度的益处,但并没有影响所有风险因素. 需要进一步的研究来确定最佳的剂量和治疗肥胖相关的非传染性疾病的疗效.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 心血管研究研究心血管研究
背景情况:
- 植物中的一种化合物白醇具有潜在的抗氧化和抗炎作用.
- 关于白醇对与肥胖有关的疾病的疗效的证据是不一致的.
- 商用白醇产品的质量,剂量和成本各不相同.
研究的目的:
- 综合来自随机对照试验 (RCT) 关于白醇对肥胖相关代谢障碍的成年人影响的证据.
- 澄清白醇在管理与肥胖相关的非传染性疾病 (NCD) 中的潜在益处和局限性.
主要方法:
- 系统地搜索PubMed,Embase,Cochrane图书馆和科学网络的RCT文献,直到2025年7月.
- 研究选择和数据提取遵循PRISMA 2020指南.
- 使用随机效应模型进行元分析,以汇集估计并评估异质性.
主要成果:
- 分析了40个带有2551名参与者的RCT.
- ресвератрол显著降低了胰岛素抵抗 (HOMA-IR),总胆固醇,甘油三,LDL胆固醇,血压,hs-CRP,TNF-α和IL-6.
- 没有观察到HDL胆固醇,体重,BMI,脂肪质量或肝酶的显著变化.
结论:
- 复星补充剂在特定的代谢和炎症标志物中显示出适度的改善.
- 它在所有与肥胖相关的NCD风险因素中没有显示广泛的有效性.
- 需要进一步的大规模,长期的RCT来确定最佳剂量和临床效用.
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