寻找关于类风湿性关节炎有意义的报告措施的共识:修改后的Delphi研究的结果
Autumn D Zuckerman1, Karen C Thomas2, Mary-Haston Vest3
1Vanderbilt Specialty Pharmacy, Vanderbilt University Medical Center, Nashville, TN.
Journal of managed care & specialty pharmacy
|February 27, 2026
概括
通过专家共识确定了类风湿性关节炎 (RA) 管理的标准化专业药房措施. 这些核心和范围的措施旨在改善患者护理和药物管理.
科学领域:
- 类风湿病学 类风湿病学
- 药房实践 在药房实践.
- 健康 结果 研究 研究 结果
背景情况:
- 专业药房收集大量数据,但很少用于绩效评估或临床决策.
- 标准化措施对于基准测试,基于绩效的合同和优化高成本药物使用至关重要.
- 改善患者护理和药物管理需要更好地利用收集的数据.
研究的目的:
- 为了在专业药房的利益相关者之间就管理类风湿性关节炎 (RA) 患者的基本和实际措施达成共识.
- 为参与RA护理的专业药房确定关键绩效指标.
主要方法:
- 一个经过修改的Delphi研究涉及25个站点和来自不同RA背景的专家小组成员,在三个调查轮中进行了调查.
- 环境扫描确定了最初的措施,随后进行了利克特尺度对重要性和可用性的评级.
- 专业药房小组成员评估了可行性,最终分类为核心,覆盖范围或没有.
主要成果:
- 315名被招募的小组成员中,有118人参加,在各轮 (73-83%) 的高响应率.
- 在13项重要和可用的措施上达成共识.
- 确定了七项核心措施 (坚持,不良反应,治疗反应,停药,切换,结核病/乙肝查) 和六项覆盖范围措施.
结论:
- 在管理RA患者的专业药房的13项关键措施上达成共识.
- 大多数确定的措施被专业药剂师认为适度到非常可行.
- 这些标准化措施可以提高专业药房的表现和RA患者的治疗结果.
相关概念视频
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
782
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
782
Genome-wide Association Studies-GWAS
16.0K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
16.0K
Rheumatic Heart Disease III: Medical Management
422
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
422
The JAK-STAT Signaling Pathway
13.4K
Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as SH2...
13.4K
Rheumatic Heart Disease IV: Nursing Management
388
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
388
Rheumatic Heart Disease I: Introduction
647
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
647


