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Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Updated: May 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

使用基于二维TMDCs的SPR生物传感器增强尿液葡萄糖传感.

Biswajit Dey¹, Md Tawabur Rahman², Arnab Saha¹

¹Department of Electrical and Electronic Engineering, Khulna University of Engineering & Technology, Khulna, 9203, Bangladesh.

Scientific reports

|February 27, 2026

概括

此摘要是机器生成的。

一种新型的表面等离子体共振 (SPR) 生物传感器使用二维 (2D) 过渡金属二甲基化物 (TMDC) 增强了尿液葡萄糖检测灵敏度. 基于MoS2的传感器为糖尿病人和非糖尿病人提供了准确的,无标签的监测.

关键词:

双金属式双金属式生物传感器是一种生物传感器.在FDTDD中,它是最重要的.表面等离子体共振是什么?TMDCs 是一个TMDC.尿液中的葡萄糖.

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FIBS-enabled Noninvasive Metabolic Profiling

FIBS-enabled Noninvasive Metabolic Profiling

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Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

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Published on: December 8, 2023

相关实验视频

Last Updated: May 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

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Published on: June 1, 2012

FIBS-enabled Noninvasive Metabolic Profiling

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Published on: February 3, 2014

Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging

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Published on: December 8, 2023

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
材料科学材料科学材料科学

背景情况:

表面等离子体共振 (SPR) 传感对于生物医学应用至关重要.
传统的SPR传感器在精确检测时的灵敏度受到限制.
开发增强的SPR生物传感器对于改善诊断能力至关重要.

研究的目的:

提出和优化基于双金属/2D过渡金属二化物 (TMDC) 的SPR生物传感器.
为了提高尿液葡萄糖检测的灵敏度和准确性.
调查不同TMDC材料在SPR传感性能中的作用.

主要方法:

利用Lumerical的有限差异时间域 (FDTD) 平台进行传感器设计和模拟.
嵌入了各种TMDC (WS2,WSe2,MoS2,MoSe2,MoTe2) 在双金属结构 (CaF2-Ag-Al) 中.
分析了电场分布和折射率变化,用于性能评估.

主要成果:

优化的CaF2-Ag-Al-MoS2结构显示出更高的灵敏度.
成功检测了非糖尿病人和糖尿病人的尿液葡萄糖度在相关范围内.
实现了高灵敏度 (455.83度/RIU),准确度 (1.32) 和质量因子 (110.10 RIU-1).
由于光学吸收和表面与体积的比率,TMDC的集成显著提高了灵敏度.

结论:

开发的SPR生物传感器与MoS2提供了一个有前途的方法,用于敏感和准确的尿液葡萄糖检测.
该传感器提供了一种无标签,具有成本效益的方法,用于非侵入性血糖监测.
这项技术有可能在糖尿病管理和诊断中得到广泛应用.