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T型Ca2+通道的阻塞通过抑制PI3K/AKT通路来破坏线粒体功能和卵泡发育

Xiuling Zhao1, Lei Wang1, Shiqin Huang1

  • 1Institute of Reproductive Medicine, Medical School, Nantong University, Jiangsu 226019, China.

Reproduction (Cambridge, England)
|February 28, 2026
PubMed
概括

一种T型通道阻塞剂Flunarizine (FNZ) 通过破坏信号传递和激活DNA损伤途径,损害了小鼠的卵巢功能和卵泡发育. 这凸显了T型通道在生殖健康中的作用.

关键词:
一个FGF1的FGF1.弗卢纳里辛 (Flunarizine) 是一种药物.细胞中的花质细胞.线粒体中的线粒体.卵巢 卵巢 卵巢 卵巢在PI3K/AKT中使用.

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