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Updated: Mar 1, 2026

Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
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针对高致病性禽流感A(H5) 病毒的候选疫苗病毒的开发和表征 病毒用于快速的流行病响应

Li Wang1, Jieru Wang1, Jaber Hossain1

  • 1Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

The Journal of infectious diseases
|February 28, 2026
PubMed
概括

高致病性禽流感A(H5) 病毒是一个流行病威胁. 美国疾病预防控制中心 (CDC) 开发了候选疫苗病毒 (CVVs),以应对对人类感染负责的A ((H5N1) 类.

关键词:
这是一种H5N1流感.交叉反应性 交叉反应性抑制血液凝结的抑制作用全球疫情防控准备工作疫苗 疫苗 疫苗 疫苗

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Viral Mutations00:36

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A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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