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Updated: Mar 1, 2026

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形成的S-甲基二 Ester 揭示了早期的生物合成步骤的雅塔基米辛

Jin Feng1, Shichao Wang1, Xu Yang1

  • 1Key Laboratory of Glyco-drug Research of Zhejiang Province, School of Chemistry and Material Sciences, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences (CAS), Hangzhou, China.

Angewandte Chemie (International ed. in English)
|February 28, 2026
PubMed
概括

雅塔基生物合成涉及硫转移和S-甲基化,需要先前的O-甲基化步骤. 这项研究阐明了一种新型S-甲基转移酶的机制,促进了对这种复杂抗生素的理解.

关键词:
它们是S-甲基 thioesters.生物合成生物合成甲基转移酶的使用方法含有硫碳酸盐的抗生素的抗生素.雅塔克米锡尼的情况

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