黄/黄补充剂对糖尿病患者功能的影响:随机对照试验的系统审查和元分析
1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Endocrinology, diabetes & metabolism
|February 28, 2026
概括
黄和黄补充剂显著降低糖尿病患者的尿素水平. 然而,它们不会显著影响肌素,血液尿素 (BUN),尿酸或白蛋白,需要进一步研究.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 黄和黄正在研究脏保护作用.
- 关于它们对糖尿病患者功能影响的证据不一致.
研究的目的:
- 系统地评估黄/黄对糖尿病患者功能的影响.
- 评估对血清肌素,BUN,尿酸,尿素和白蛋白的影响.
主要方法:
- 12项随机对照试验 (RCT) 的系统性审查和元分析,涉及1303名参与者.
- 搜索了PubMed,科学网络和Scopus数据库.
- 使用随机效应模型分析数据,评估偏差风险和证据确定性 (GRADE).
主要成果:
- 黄/黄并没有显著改变肌素,BUN或白蛋白水平.
- 观察到尿酸减少的趋势 (p=0.053).
- 尿素水平显著降低 (WMD: -2.53 mg/dL,p=0.002). 尿素含量显著降低 (WMD: -2.53 mg/dL,p=0.002). 发布偏差检测到肌氨酸.
结论:
- 黄/黄补充剂在糖尿病患者中有效降低尿素.
- 没有发现对其他关键功能标志物的显著影响.
- 需要高质量的长期RCT来确认保护潜力和最佳剂量.
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