纤维内生长:艾哈迈德玻璃眼的一个被忽视的原因门失效
Shahin Yazdani1,2, Neda Einollahi3,4,5, Azadeh Doozandeh1,2
1Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
概括
纤维生长 (FI) 进入艾哈迈德玻璃眼 (AGV) 是AGV故障的常见原因. 在修复手术期间手术切除FI有效降低眼内压力并恢复AGV功能.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 医疗器械研究 医疗器械研究
背景情况:
- 由于各种因素,艾哈迈德玻璃眼 (AGV) 植入物的晚期失效可能发生.
- 纤维生长 (FI) 进入AGV机制是设备故障的一个未被认可的原因.
- 了解FI的作用对于改善青光眼治疗结果至关重要.
研究的目的:
- 识别和突出艾哈迈德玻璃眼 (AGV) 中的纤维生长 (FI) 作为晚期AGV故障的重要原因.
- 评估手术修复的疗效,包括去除FI.
- 为了比较FI和没有FI的患者在修复手术后的结果.
主要方法:
- 一个潜在的干预病例系列,涉及40名失败的AGV患者,他们正在接受囊切除术分流修订 (CSR).
- 在手术期间对AGV门机制进行探索,以确定纤维组织的生长.
- 将患者分为有 (FI-CSR) 和没有 (CSR) 纤维内生长的群体.
- 评估手术前和后的眼内压 (IOP),药物使用,并发症和手术成功.
主要成果:
- 在30%的眼部手术中发现了纤维内生长 (FI).
- 患有FI的患者年龄较大,先前接受过更多的手术,患初级先天性玻璃眼的患病率更高.
- 无论是FI-CSR还是CSR组,在修订后12个月内,IOP均显著减少 (P < 0.001).
- 在这两组人群中,手术成功率和最终的IOP是可比的.
- 组织病理学揭示了切除FI的密集的纤维血管组织与慢性炎症.
结论:
- 纤维入AGV门腔是一个重要的,经常被忽视的AGV故障原因.
- 在CSR期间手术切除FI,恢复器件功能并改善IOP控制,结果与传统的CSR相提并论.
- 在修复手术期间探索用于FI检测和移除的门机制是有益的,并可能防止更具侵入性的手术.
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