Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Assumptions of Survival Analysis01:15

Assumptions of Survival Analysis

467
Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
467
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

674
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
674
Introduction To Survival Analysis01:18

Introduction To Survival Analysis

894
Survival analysis is a statistical method used to study time-to-event data, where the "event" might represent outcomes like death, disease relapse, system failure, or recovery. A unique feature of survival data is censoring, which occurs when the event of interest has not been observed for some individuals during the study period. This requires specialized techniques to handle incomplete data effectively.
The primary goal of survival analysis is to estimate survival time—the time...
894
Survival Tree01:19

Survival Tree

451
Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
 Building a Survival Tree
Constructing a...
451
Parametric Survival Analysis: Weibull and Exponential Methods01:14

Parametric Survival Analysis: Weibull and Exponential Methods

1.2K
Parametric survival analysis models survival data by assuming a specific probability distribution for the time until an event occurs. The Weibull and exponential distributions are two of the most commonly used methods in this context, due to their versatility and relatively straightforward application.
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
1.2K
Kaplan-Meier Approach01:24

Kaplan-Meier Approach

663
The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
663

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Comparative evaluation of low-temperature storage strategies for fresh beef: Insights into physicochemical quality, microstructure, and bacterial community.

Food research international (Ottawa, Ont.)·2026
Same author

Constructing Mo-O-Ni anchoring bonds by room temperature solid-state reduction to drive hydrogen spillover for saturated hydrogenation of naphthalene.

Chemical communications (Cambridge, England)·2026
Same author

Giant Bulk Photovoltaic Effect in Two-Dimensional Topological Ferroelectric Semimetal.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

In-plane anomalous Hall effect in hard magnetic Weyl semimetal Co<sub>3</sub>Sn<sub>2</sub>S<sub>2</sub>.

Journal of physics. Condensed matter : an Institute of Physics journal·2026
Same author

Laser-Induced Spin-Lattice Coupling and the Emergence of Ferrimagnetic State in Kagome Metal RbV<sub>3</sub>Sb<sub>5</sub>.

ACS nano·2026
Same author

The pivotal regulatory factor circ_0006956 promotes arsenic-induced lung carcinogenesis by enhancing the Warburg effect.

Chemico-biological interactions·2026

相关实验视频

Updated: Mar 1, 2026

Establishing a Competing Risk Regression Nomogram Model for Survival Data
04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.9K

对于具有竞争风险的离散时间生存模型的最佳设计.

XiaoDong Zhou1, YunJuan Wang2, RongXian Yue3

  • 1School of Statistics and Data Science, Shanghai University of International Business and Economics, Shanghai, 201620, China.

Lifetime data analysis
|February 28, 2026
PubMed
概括

这项研究介绍了随机生存试验的最佳设计,该试验具有多个竞争事件. 对于具有竞争风险的离散时间到事件试验,平等的组分配通常是最好的.

关键词:
竞争的风险 竞争的风险离散时间生存模型.纵向研究是一项纵向研究.参数竞争风险模型的参数竞争风险模型.时间变化的治疗效果.

更多相关视频

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

2.7K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

956

相关实验视频

Last Updated: Mar 1, 2026

Establishing a Competing Risk Regression Nomogram Model for Survival Data
04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.9K
An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

2.7K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

956

科学领域:

  • 生物统计学 生物统计学
  • 临床试验设计 临床试验设计
  • 生存分析的分析.

背景情况:

  • 随机对照试验 (RCT) 设计研究往往忽视了多个竞争的终点.
  • 许多临床试验面临着多个目标事件的挑战,缺乏最佳设计策略.
  • 现有的统计文献还没有系统地解决与竞争事件相匹配的生存试验的最佳设计.

研究的目的:

  • 开发用于随机分离时间到事件试验的设计方法,具有竞争的终点.
  • 解决与多个竞争目标事件的试验的最佳设计策略的差距.
  • 在如此复杂的试验环境中确定最佳设计来估计治疗效果.

主要方法:

  • 通过将数据转换为多项反应,为离散时间生存模型 (DTSM) 导出了费舍尔信息矩阵.
  • 引入了基于成本的通用最佳设计标准,以确定最佳设计.
  • 假设基本生存过程的参数竞争风险模型.

主要成果:

  • 最佳治疗分配方案受到竞争风险模型中的参数值的显著影响.
  • 证明在具有竞争风险的双臂DTSM试验中,平等的受试者分配通常是有利的.
  • 确定了平等分配可能不是最佳的例外情况,特别是当危险率较低时.

结论:

  • 开发的方法为具有竞争终点的离散时间到事件试验提供了最佳的设计策略.
  • 这些发现为设计具有多重竞争风险的临床试验提供了实际指导.
  • 该研究强调了在试验设计和分配策略中考虑竞争事件的重要性.