亚地诺病毒通过触发巨细胞两极分化和通过NF-κB激活激发IL-6的产生诱导儿科肺炎

Xiaoping Yuan1, Haoying Huang2, Huifeng Fan3

  • 1Department of Respiratory Medicine, School of Pharmaceutical Sciences, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Research Center for Child Health, Guangzhou 510623, China; Guangzhou Women and Children's Medical Center, Guangdong Provincial Research Center for Child Health, State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou 510623, China.

Molecular immunology
|February 28, 2026
PubMed
概括

儿童感染人类腺病毒 (HAdV) 驱动M1巨细胞两极分化,通过NF-κB信号增加IL-6的产生. 这种机制有助于HAdV肺炎中严重的肺损伤.

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