孕前母亲的体重指数,妊娠期体重增加和后代的:基于人口的队列研究
Jiawen Chen1, Haoran Zhuo2, Tormod Rogne3
1Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA.
Epilepsy research
|February 28, 2026
概括
孕前母亲的超重和肥胖与患儿的风险更高有关. 然而,妊娠期体重增加模式并未显示出与后代风险的明显关联.
科学领域:
- 生殖健康 生殖健康
- 儿科神经学 儿科神经学
- 公共卫生 公共卫生
背景情况:
- 孕前母亲的体重指数 (BMI) 和孕期体重增加 (GWG) 是影响怀孕结果和后代健康的关键因素.
- 是一种常见的儿童神经系统疾病,具有复杂的病因.
- 了解可修改的孕产妇因素可能为预防提供途径.
研究的目的:
- 调查母亲怀孕前BMI类别和非最佳GWG与儿童风险之间的关联.
- 在加利福尼亚州的一大批活产婴儿中分析这些关联.
主要方法:
- 一项基于人口的队列研究,对2007年至2015年间出生的3,816,438名儿童进行了研究.
- 儿童通过诊断记录确定.
- 用于估计风险比率 (RR) 和95%置信区间 (CI) 的通用线性模型,对混因素进行调整.
主要成果:
- 孕前母亲的超重 (RR: 1.12) 和肥胖 (RR: 1.31) 与儿童风险增加有关.
- 在GWG不足或过量与儿童之间没有发现显著的关联.
- 妊娠期体重减轻显示在超重/肥胖母亲的后代中与有关,但这在到期分娩中没有显著意义.
结论:
- 孕前母亲的超重和肥胖与儿童有轻微的关联.
- 不理想的妊娠期体重增加,包括体重减轻,不足或过度增加,并没有与儿童风险有明显的关联.
更多相关视频
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
5.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.2K
Epilepsy and Seizures: Overview
1.5K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.5K
Pathophysiology of Diabetes
3.9K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.9K
Obesity
1.4K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.4K
Seizures: Classification
1.9K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
1.9K


