对于患有克朗氏病的成年人,固体食物的饮食干预:从范围审查中获得的方法见解
Konstantina Morogianni1, Dimitrios Karayiannis2, Avra Almperti2
1Laboratory of Dietetics and Quality of Life, Department of Food Science and Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, Athens 11855, Greece.
Nutrition reviews
|February 28, 2026
概括
全食饮食对克罗恩氏病 (CD) 管理有希望,但研究差异很大. 本次审查强调了当前研究中的方法不一致性,呼吁采用标准化的方法来更好地了解饮食.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 证据综合 证据综合
背景情况:
- 固体食品饮食越来越多地被探索用于管理克罗恩病 (CD).
- 关于CD全食干预的现有研究是有限的,并且在方法上是异质的.
- 了解这些饮食的营养方面和方法严谨性至关重要.
研究的目的:
- 综合分析成年CD患者全食饮食干预措施的方法方面.
- 描述实施的饮食干预措施的营养含量和充分性.
- 识别当前研究方法的挑战和不一致性.
主要方法:
- 对成年CD患者的固体食物饮食进行的干预研究进行范围审查.
- 在PubMed,Scopus和CENTRAL数据库中进行的搜索截至2025年7月.
- 纳入标准集中在积极或缓解的CD患者的明确固体饮食干预措施上.
主要成果:
- 包括23项研究 (15项RCT,2项试点RCT,5项前性,1项非随机).
- 在13项研究中评估了营养状况/充分性;在大多数研究中报告了坚持.
- 实际的营养摄入量和充足性很少被评估.
结论:
- 对于成年CD的固体食品饮食试验存在重大方法挑战.
- 研究设计,参与者标准和结果指标的变化很普遍.
- 需要标准化的方法来加强有关饮食在疾病管理中的作用的证据.
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