空气污染和慢性咳之间的关联:来自观察性研究的系统审查和元分析的证据
Hyejun Kim1, Kefang Lai2, Tariq Cisse3
1Dalla Lana School of Public Health, University of Toronto, Ontario, Canada.
Environmental research
|February 28, 2026
概括
空气污染,包括细颗粒物 (PM2.5) 和二氧化 (NO2),与慢性咳有关. 医疗保健专业人员应考虑环境因素来控制持续咳,以防止严重的呼吸系统问题.
科学领域:
- 环境健康 环境健康
- 呼吸系统医学 呼吸系统医学
- 流行病学 流行病学
背景情况:
- 慢性咳是一种普遍的,使人致残的呼吸系统症状.
- 空气污染和慢性咳之间的联系需要进一步调查.
研究的目的:
- 系统地审查和对空气污染和慢性咳之间的关联进行观测研究进行元分析.
- 量化与特定空气污染物相关的慢性咳风险.
主要方法:
- 53项审查研究的系统审查和元分析 (8项纳入元分析).
- 在主要数据库中进行的搜索截至2025年2月14日.
- 随机效应模型用于计算空气污染暴露的聚合概率比率 (ORs).
主要成果:
- 增加暴露于PM2.5 (OR 1.10每10μg/m3;95%CI:0.99-1.22) 和NO2 (OR 1.04每10μg/m3;95%CI:1.02-1.06) 与慢性咳相关.
- 观察到低到中等的异质性和没有出版偏差.
- 在成人和男性中发现更强烈的关联;关于进展到严重呼吸道疾病的证据有限.
结论:
- 慢性咳是空气污染暴露的一个未被认可的结果.
- 医疗保健提供者应将环境评估纳入慢性咳管理中.
- 加强空气质量控制和早期检测对于减少呼吸道疾病负担至关重要.
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