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组认知行为疗法与跨直接电流刺激相结合:青少年抑郁症临床随机对照试验

Jingjing Feng¹, Xuejie Ye¹, Xiaoli Liu¹

¹Department of psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo 315201, Zhejiang, China; Department of psychiatry, Ningbo Kangning Hospital, Ningbo 315201, Zhejiang, China.

Biological psychiatry. Cognitive neuroscience and neuroimaging

|February 28, 2026

概括

将群体认知行为疗法 (GCBT) 与直流刺激 (tDCS) 结合起来,可显著改善青少年抑郁症症状. 这种新的方法为与抑郁症作斗争的年轻人提供了更有效的治疗选择.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
临床心理学临床心理学

背景情况:

青少年抑郁症是一个普遍存在的心理健康问题.
现有的治疗方法,如群体认知行为疗法 (GCBT) 和跨直流刺激 (tDCS),其有效性有限,开始缓慢.
综合方法可以提供增强的治疗效益.

研究的目的:

调查结合GCBT与tDCS治疗青少年抑郁症的疗效.
为了比较与GCBT一起使用的活性tDCS与假冒tDCS的有效性.

主要方法:

一个随机的,单盲的,假控制的试验,涉及67名被诊断患有抑郁症的青少年.
参与者与GCBT同时接受了为期五周的活跃或虚假tDCS.
使用汉密尔顿抑郁评分表 (HDRS-24) 和自我评分抑郁评分表 (SDS) 评估治疗前后的抑郁症状.

主要成果:

两只治疗手臂在SDS和HDRS-24.4上都显示出显著的症状减少.
与虚假组相比,接受GCBT与活性tDCS的组在SDS和HDRS-24分数中表现出更好的改善.
在活跃的tDCS组 (48.49%) 与假装组 (25.00%) 相比,观察到更高的临床响应率.

结论:

将GCBT与tDCS结合起来是治疗青少年抑郁症的可行和有效干预措施.
这种联合疗法显著缓解了抑郁症状.
这些发现支持GCBT加tDCS在青少年抑郁症的潜在临床应用.

关键词:

青少年抑郁症青少年抑郁症团体认知行为疗法团体认知行为疗法 tDCSCS 是一个很好的方法.

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