与老年人术后认知结果相关的心理因素:系统性审查和元分析
Anahita Amirpour1, Lina Bergman1, Jeanette Eckerblad1
1Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
British journal of anaesthesia
|February 28, 2026
概括
手术前的抑郁症与老年人手术后的妄想有关. 需要进一步的研究来了解焦虑,个性和压力对认知结果的影响.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
背景情况:
- 老年人患术后认知并发症的风险更高,影响恢复.
- 手术前的心理因素可能会影响这些结果,但其作用尚未完全理解.
研究的目的:
- 在老年人中,系统地审查和元分析术前心理因素与术后认知结果之间的关联.
主要方法:
- 30项60岁以上的研究 (6714名受试者) 的系统审查和元分析.
- 搜索了五个数据库;使用纽卡斯尔-太华尺度或Cochrane偏差风险2.0.0评估研究质量.
- 在可行的情况下,进行随机效应元分析,并补充P值综合和投票计数.
主要成果:
- 抑郁症是最常见的与术后妄想相关的心理因素.
- 分析显示,抑郁症和术后妄想之间没有显著的关联 (OR 1.08).
- 没有元分析的综合表明,在28项研究中,心理因素和认知结果之间存在显著的关联 (P<0.001).
结论:
- 抑郁症是老年人术后痴呆症的一个显著的心理风险因素.
- 目前对焦虑,人格特征和压力的证据有限.
- 建议进行标准化的认知评估和干预研究以改善结果.
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