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[患有囊性纤维化儿童的听力损伤]

A I Kryukov¹, A Yu Ivoilov¹, N A Mileshina²

¹Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia.

Vestnik otorinolaringologii

|March 1, 2026

概括

囊性纤维化患者可能会因氨基糖类抗生素而出现听力损失. 炎症问题也导致囊性纤维化儿童的听力损伤,需要进一步的听力功能研究.

科学领域:

儿科耳鼻喉科儿科耳鼻喉科
医学遗传学医学遗传学
药理学药理学是指药理学的学科.

背景情况:

听力障碍是患有囊性纤维化 (CF) 的儿童的一个重大问题.
系统性抗菌疗法,特别是氨基糖类抗生素,经常用于CF治疗.
氨基甘油酸的耳毒作用对这种脆弱人群的听觉功能构成风险.

研究的目的:

为了调查患有囊性纤维化症的儿童听力损失的原因.
分析氨基糖化物抗生素治疗对儿科CF患者听觉功能的影响.
为了确定这个群体中听力障碍的特定风险因素.

主要方法:

进行了全面的文献搜索.
使用的数据库包括PubMed,科学网络和eLibrary.
审查重点关注了与CF及其治疗相关的检查听力功能的研究.

主要成果:

氨基糖化物使用与CF患者的感觉神经听力损失有关.
中耳和欧斯塔基管中的炎症过程预测导电性听力损失.
氨基糖化物治疗并不总是导致听力损伤,突出显示了个体的变化.

结论:

进一步的研究对于了解CF儿童听力损失的细微差别至关重要.
识别听力损失的特定特征可以为有针对性的干预提供信息.
监测听力功能对于接受囊性纤维化治疗的儿童至关重要.

关键词:

氨基甘油酸氨基化物.传导性听力损失是指传导性听力损失.囊性纤维化症是什么在儿童中听力损伤.感应神经神经听力损失

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