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Updated: Mar 2, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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在DNA复制和重组中评估非正规的p53功能,用于变体分类

Rebecca Jansche1, Benedikt Heitmeir1, Ulrike Faust2

  • 1Department of Obstetrics and Gynecology, Ulm University, Ulm, Germany.

Cell death & disease
|March 1, 2026
PubMed
概括

这项研究研究了TP53变体,发现重组试验可以帮助分类未知意义的变体. 一些以前未经分类的变体显示出明显的良性或致病模式,有助于对Li-Fraumeni综合征的风险评估.

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