针对左背侧前额叶皮层的高清超直流刺激,以修改社会焦虑的年轻成年人的认知偏差:一项随机对照试验
Yi Yu1,2, Hui Yu3, Rumiao Pan2
1Institute of Psychological and Brain Sciences, Liaoning Normal University, Dalian, 116029, China.
Molecular psychiatry
|March 1, 2026
概括
在左脊侧前额叶皮层进行高清横直流刺激 (HD-tDCS) 改善了社会焦虑的年轻成年人的认知偏差. 然而,自我报告的症状没有显著变化,这表明有针对性的大脑刺激影响行为比有意识的经验更多.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 精神病学是一个精神病学.
背景情况:
- 社会焦虑障碍 (SAD) 是通过注意力,解释和记忆的认知偏见来维持的.
- 抑郁症的神经机制包括杏仁核过度激活,默认模式网络活动和前额叶皮层失调.
研究的目的:
- 调查线下高清跨直流刺激 (HD-tDCS) 对具有社会焦虑的年轻成年人的认知偏差的影响.
- 评估HD-tDCS针对左背侧前额皮质 (DLPFC) 对注意力,解释和记忆偏差的影响.
主要方法:
- 74名具有高度社会焦虑的大学生被随机分配到活跃的HD-tDCS或假控制组.
- 参与者在连续五天内接受了10次20分钟的阳节刺激,以左侧DLPFC为目标.
- 认知偏见和社会焦虑症状被评估,使用行为任务和自我报告措施进行干预前后的评估,随访1个月.
主要成果:
- 离线HD-tDCS在左边的DLPFC显著改善了注意力回避,负面解释偏差和负面记忆偏差的行为指标.
- 在随访时,在自我报告的社会焦虑症状或认知偏见方面,没有发现群体之间的显著差异.
- 行为认知偏差的改善至少在刺激后的短期内持续存在.
结论:
- 针对左侧DLPFC的HD-tDCS显示出调节与年轻成年人社会焦虑相关的行为认知偏见的潜力.
- 观察到的行为影响并没有转化为自我报告症状的显著变化,这表明隐性和显式措施之间的分离.
- 需要进一步的研究来探索HD-tDCS对社会焦虑障碍的临床效用和长期影响.
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