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Updated: Mar 2, 2026

Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis
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通过对接和分子动力学模拟揭示CD36细胞表面受体的小分子结合部位

Naomi Montes-Mondragón1, Rosa Salgado-Brito1, José-Rubén García-Sánchez2

  • 1Universidad Simón Bolívar, Av. Río Mixcoac Nº 48, Col. Insurgentes, Mixcoac, Benito Juárez, Ciudad de México C.P. 03920, México.

Current medicinal chemistry
|March 1, 2026
PubMed
概括

这项研究揭示了CD36的关键结合部位,包括小分子受体腔 (SMAC),这对于理解长链脂肪酸 (LCFA) 吸收至关重要. 这些发现为开发代谢疾病和癌症的新疗法提供了洞察力.

关键词:
CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36 CD36绑定网站 绑定网站对接和MD模拟的对接和MD模拟.脂肪酸 脂肪酸 脂肪酸 脂肪酸血小板. 血小板. 这是.它们是小分子.

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