癌症患者蛋白质摄入量的来源和分布模式:通过组成数据分析与肌肉质量和力量的关联
Jia-Xin Huang1, Si-Wei Xie2, Hui-Min Qu3
1Comprehensive Oncology Department, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Clinical nutrition (Edinburgh, Scotland)
|March 1, 2026
概括
蛋白质来源和分布影响癌症患者的肌肉质量和力量. 最佳摄入量和特定来源,如乳清,家禽和红肉与更好的肌肉结果有关.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 老年学是指老年学的学科.
背景情况:
- 肌肉质量和功能丧失的萨尔科佩尼亚,在癌症患者中很常见.
- 了解蛋白质摄入量对于管理这种人群的肌肉健康至关重要.
研究的目的:
- 研究癌症患者的蛋白质摄入来源和分布.
- 分析蛋白质摄入模式与肌肉质量/力量之间的关联.
主要方法:
- 一项对中国5079名癌症患者进行的纵向队列研究.
- 患者按每日蛋白质摄入量 (低,中等,充足,高) 分层.
- 评估了肌肉结果 (FFMI,HGS);使用回归和组成数据分析分析了关联.
主要成果:
- 饮食中的蛋白质是主要来源 (87.30%);红肉占主导地位.
- 乳清蛋白摄入量与较高的无脂肪质量指数 (FFMI) 相相关.
- 禽肉和红肉摄入量与FFMI和手握强度 (HGS) 有积极的关联.
结论:
- 蛋白质来源及其时间影响癌症患者的肌肉质量和力量.
- 特定的蛋白质类型和饮食模式是肌肉健康管理的关键.
相关概念视频
Overview of Protein Metabolism
4.3K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
4.3K
Proteins: Dietary Sources and Requirements
1.9K
Consuming animal-based products offers high-quality proteins that contain optimal levels and combinations of essential amino acids, crucial for tissue repair and growth. Foods like eggs, milk, fish, and most meats are a source of complete proteins. Legumes and cereals are abundant in proteins; however, they typically lack a full range of essential amino acids. As a result, they are considered incomplete protein sources. Some plant sources like soybeans, quinoa, and amaranth do contain complete...
1.9K
Protein Networks
4.6K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.6K
mTOR Signaling and Cancer Progression
4.9K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
The mTOR pathway or the...
4.9K
Cancer Survival Analysis
805
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
805


