清细胞细胞癌 (ccRCC) 中的Hippo通路:与VHL破坏的联系?

T Waeckel1, R Lefranc1, M Waeckel2

  • 1Université de Caen Normandie, CNRS, Normandie Univ, ISTCT UMR6030, CYCERON, F-14000 Caen, France; Centre Hospitalier Universitaire de Caen Normandie, Service d'Urologie et Transplantation, 14000 CAEN, France.

PubMed
概括

在清细胞细胞癌 (ccRCC) 中,Hippo路径发生变化,影响瘤进展和存活率. 准Hippo-VHL轴为ccRCC患者提供了新的生物标志物和治疗方法.

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