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Updated: Mar 3, 2026

Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
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费诺纤维酸向PPARα-CPT1C轴,通过调节脂质代谢和线粒体功能来逆转衰老

Yanying Zhou1, Yixin Chen2, Linlin Zhu3

  • 1NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hong Kong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.

Pharmacological research
|March 1, 2026
PubMed
概括

费诺纤维酸是一种超脂血症药物,通过向脂质积累和线粒体功能障碍,显示出显著的抗衰老作用. 它的益处是通过氧酶增殖器激活受体α (PPARα) - 卡尼丁棕甲基转移酶1C (CPT1C) 轴介导的.

关键词:
衰老的衰老 衰老的衰老卡尼丁棕甲基转移酶1C菲诺纤维酸盐的使用方法脂质的积累 脂质的积累线粒体代谢的代谢过程Peroxisome增殖器激活受体 α 的受体.

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