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氨基酸β聚合物通过铁死在大脑内皮细胞中诱导血管病变

Suhyeon Son1, Suji Kim1, Min-Tae Jeon1

  • 1Dementia Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.

Brain pathology (Zurich, Switzerland)
|March 1, 2026
PubMed
概括

阿尔茨海默病的粉样β斑块通过引起脂质过氧化,在脑细胞中触发铁. 抑制这种途径减少了粉样β,为阿尔茨海默病提供了潜在的治疗点.

关键词:
粉样蛋白-βββββββββββββββββββββββββββββββββββββββββββββββββββββββββ血脑屏障 血脑屏障 血脑屏障铁性化 (ferroptosis) 是一种脂质滴滴滴滴滴滴滴滴滴滴滴滴滴脂质过氧化过氧化

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