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Updated: Mar 3, 2026

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[MUC1和SIGIRR作为TLR信号的负调节者:表达,功能和抗炎增强]

Keiko Ueno-Shuto1

  • 1Faculty of Pharmaceutical Sciences, Sojo University.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
|March 1, 2026
PubMed
概括

菌素-1 (MUC1) 和单个免疫球蛋白互白素-1相关受体 (SIGIRR) 调节了托尔类受体 (TLR) 信号传递. 研究表明,MUC1抑制TLRs,而LPS-TLR4-p38信号减少SIGIRR,影响抗炎途径.

关键词:
互乐金-18受体α是一个α.介质素-37-37 介质素-37 介质素-37 介质素-37这就是"mucin-1".托尔类受体信号传递的负调节器.单个免疫球蛋白互白素-1相关受体.

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