[中国克隆病的流行病学,致癌性,预防和控制]
1Department of Epidemiology, Faculty of Navy Medicine, Naval Medical University, Shanghai 200433, China Key Laboratory of Biological Defense, Ministry of Education, Shanghai 200433, China Shanghai Key Laboratory of Medical Bioprotection, Shanghai 200433, China.
概括
克隆病是由寄生虫Clonorchis sinensis引起的,在中国感染了数百万人. 有效的控制需要一个综合的"一健康"方法,包括新的疫苗,以对抗这种食源性动物性传染病.
科学领域:
- 动物传染病寄生虫疾病
- 食物传播疾病 食物传播疾病
- 公共卫生 公共卫生
背景情况:
- 克隆诺基亚病是一种流行的食物传播动物性疾病,主要是由Clonorchis sinensis引起的.
- 2020年,中国报告了大约946万例感染病例,近1亿人处于危险之中.
- 寄生虫的复杂生命周期带来了控制挑战.
研究的目的:
- 突出中国Clonorchis sinensis感染对公共卫生的影响.
- 讨论Clonorchis sinensis在胆管癌发育中的作用.
- 倡导一个综合的"一健康"疾病控制战略.
主要方法:
- 关于Clonorchis sinensis流行病学和病理学的文献综述.
- 分析中国的感染数据和风险因素.
- 审查当前和拟议的控制策略.
主要成果:
- 克洛诺基斯·辛内斯是1组人类致癌物,与胆管癌有关.
- 疾病病理包括胆道阻塞,身体损伤和化学刺激.
- 综合的"一个健康"方法对于有效的管理至关重要.
结论:
- 有效的Clonorchis sinensis控制需要一个多方面的"一个健康"战略.
- 干预措施应包括化疗,健康教育和环境管理.
- 疫苗开发提供了一个有前途的新型预防措施.
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