地中海饮食和高度加工食品在炎症性肠道疾病中的作用
D Maniero1, N Pol1, C Caranfil2
1Department of Surgery, Oncology, Gastroenterology, University of Padua, Via Giustiniani 2, 35121 Padua, Italy.
概括
克罗恩病患者表现出较低的地中海饮食坚持,特别是在活跃的疾病. 更高的加工食品摄入量与IBD患者的代谢问题有关.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 炎症性肠道疾病研究研究
背景情况:
- 地中海饮食 (MD) 以其健康益处而闻名,而高度加工食品 (HPF) 可能会对代谢健康产生负面影响.
- 炎症性肠病 (IBD),包括克罗恩病 (CD) 和性结肠炎 (UC),涉及饮食和疾病活动之间的复杂相互作用.
- 了解IBD的饮食模式对于管理患者的健康和疾病结果至关重要.
研究的目的:
- 为了比较患有克罗恩病 (CD) 和性结肠炎 (UC) 的患者遵守地中海饮食 (MD) 和消费高度加工食品 (HPF).
- 研究饮食模式 (MD坚持和HPF摄入) 与IBD患者的疾病活性之间的关系.
- 探索这些饮食模式和IBD人口中的代谢参数之间的关联.
主要方法:
- 利用金字塔地中海饮食得分 (PyrMDS) 来评估MD的坚持.
- 使用高加工食品短问卷 (sQ-HPF) 来评估HPF摄入量.
- 包括193名连续IBD患者在研究队列中.
主要成果:
- 克罗恩病患者与性结肠炎患者相比,对MD的坚持明显较低 (PyrMDS中位数9.3比9.8,p=0.02).
- 在CD和UC组之间,高度加工食品的消费量是可比的 (中位数sQ-HPF3).
- 在CD患者中,一种趋势表明MD坚持和疾病活性之间的反相关性 (p = 0.07),高HPF摄入与代谢综合征有关 (中位数sQ-HPF 4对3,p = 0.01).
结论:
- 克罗恩氏病患者对地中海饮食的坚持减少,特别是当疾病活性较高时.
- 过度加工食品的摄入量增加与IBD患者的不良代谢概况相关.
- 个性化营养指导对于促进IBD患者健康饮食选择至关重要.
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