儿科造血干细胞移植患者的急性尾炎:一个单一中心的经验
Mustafa Okumuş1, Dilek Ece2, Avni Atay3
1Faculty of Medicine, Department of Pediatric Surgery, Yeni Yüzyıl University, Istanbul, Turkey.
Pediatric transplantation
|March 1, 2026
概括
早期的腹腔镜尾切除术在血造干细胞移植 (HSCT) 后患有急性尾炎的儿科患者是安全的. 这种方法有效地管理免疫功能低下儿童的尾炎,显示出良好的结果.
科学领域:
- 儿科外科手术 儿科外科手术
- 血液学 / 瘤学
- 移植医学是一种移植医学.
背景情况:
- 急性尾炎是一种罕见但严重的并发症,发生在血造细胞干细胞移植 (HSCT) 后的儿科患者身上.
- 接受HSCT的患者往往免疫受损和中性衰竭,增加与手术感染相关的风险.
研究的目的:
- 为了评估早期腹腔镜尾切除术的临床特征和结果,在儿童患者中,在HSCT后发生了急性尾炎.
- 确定腹腔镜尾切除术作为这种高风险人群的主要治疗方法的安全性和有效性.
主要方法:
- 在2015年至2025年期间,对10名儿科患者进行过全基性HSCT的回顾性单中心研究.
- 收集的数据包括人口统计,实验室值,成像,手术时间和患者结果.
- 所有患者都被诊断为急性尾炎,并在24小时内接受了腹腔镜尾切除术.
主要成果:
- 1.4% (10/737) 的儿科HSCT接受者患有急性尾炎,移植后的中位数诊断时间为23.5天.
- 常见的症状包括腹痛 (80%),吐 (50%) 和发烧 (40%);50%在诊断时严重中性衰竭.
- 早期的腹腔镜尾切除没有显示任何术后并发症,并迅速恢复口服养,并且没有手术延迟.
结论:
- 早期腹腔镜尾切除术是小儿HSCT接受者急性尾炎的安全有效治疗方法.
- 这种外科手术建议作为一线策略,即使在免疫抑制和中性衰竭患者.
- 成功管理突出了在这个脆弱的患者群体中及时进行手术的可行性.
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