审查目前对黄斑下出血的管理
Jonathan Martin1, Trisha Ortiz2,3, Sidra Zafar2
1Sidney Kimmel Medical College, Thomas Jefferson University.
Current opinion in ophthalmology
|March 2, 2026
概括
黄斑下出血 (SMH) 的管理缺乏共识. 抗VEGF治疗是关键的,肺部位移对大量出血有好处,但早期干预对于更好的结果至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 斑点退化症 斑点退化症
背景情况:
- 亚视网膜出血 (SRH) 通常是新血管与年龄相关的黄斑变性 (nAMD) 的结果.
- 通过机械,有毒和炎症损伤,SRH可以导致显著的视力丧失.
- 黄斑下出血 (SMH) 管理缺乏普遍商定的方法.
研究的目的:
- 审查SMH目前的治疗选择.
- 总结关于SMH管理的关键比较研究.
- 突出SMH治疗中持续存在的挑战.
主要方法:
- 审查关于SMH治疗的当前文献.
- 对手术和非手术干预的比较研究的分析.
- 评估辅助疗法,如复合组织等质激素激活剂 (rtPA).
主要成果:
- 抗血管内皮生长因子 (抗VEGF) 治疗是核心的,其结果与小/中等SMH的手术类似.
- 带有或没有rtPA的气动位移 (PD) 为广泛的SMH提供了最大的好处.
- 帕斯普拉纳玻璃切除术 (PPV) 是大型/耐火病例的一个选择,但并不总是优于更少的侵入性方法.
结论:
- 早期干预与更好的SMH结果有关.
- 没有一个单一的治疗算法是普遍接受的.
- 需要进一步的研究和多式联运成像来完善SMH管理策略.
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