在初级甲状腺功能过强症中,指甲毛细血管变化
Ahmet Ozcan1, Hakan Korkmaz1, Rahime Cankat Gurel2
1Department of Internal Medicine, Division of Endocrinology, Faculty of Medicine, Suleyman Demirel University, Isparta, Türkiye.
患有原发性甲状腺功能增强症 (PHPT) 的患者表现出显著的指甲毛细血管变化. 这些微血管变化与副荷尔蒙 (PTH) 和水平有关,这表明PHPT会影响周围循环.
科学领域:
- 内分泌学 在内分泌学.
- 血管生物学 血管生物学
- 皮肤病学 皮肤病学
背景情况:
- 原发性偏甲状腺症 (PHPT) 是一种常见的内分泌疾病.
- 心血管并发症在PHPT中得到识别.
- 在PHPT中,对外周微循环的变化不太了解.
研究的目的:
- 评估PHPT患者的指甲毛细血管形态.
- 调查毛细血管变化与血清偏激素 (PTH) 和水平之间的关联.
主要方法:
- 这是一项涉及62名PHPT患者和34名对照者的横截面研究.
- 数字皮肤镜用于指甲毛细血管评估.
- 测量血清中,PTH和其他生物化学标记物的水平.
主要成果:
- 在PHPT患者中,指甲毛细血管的轻微形态变化 (MiMC) 的患病率和得分显著增加.
- 血管面积得分 (AAS) 与PTH,和年龄正相关.
- 血清独立地与MiMC相关;PTH和年龄独立地影响了AAS.
结论:
- 在PHPT患者的指甲毛细血管中存在微血管变化.
- 在毛细血管水平上,PHPT可能会影响外周微循环.
- 这些发现扩大了对PHPT除了心血管参与之外的系统性影响的理解.
更多相关视频
05:17A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy
Published on: October 27, 2015
07:13Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
相关概念视频
The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Cardiovascular System Abnormal Findings I: Inspection and Palpation
Abnormal findings observed during an inspection
Skeleton and Calcium Homeostasis
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Chronic Kidney Disease II: Clinical Manifestations
