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Updated: Mar 3, 2026

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[在患有急性淋巴细胞白血病的儿童中,MTHFR基因多态与甲状腺素代谢的关联]

Xiao-Dan Wang1, Jin-Wen Li1, Ping Zhang1

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Institutes of Health Science, Tianjin 300020, China.

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
|March 2, 2026
PubMed
概括

血清甲状腺素 (MTX) 水平和MTHFR基因变异会影响高剂量的MTX代谢和ALL儿童的毒性. 监测MTX水平是关键,MTHFR遗传学作为治疗的次要指南.

关键词:
急性淋巴细胞白血病 (Acute Lymphoblastic Leukemia) 是一种急性淋巴细胞白血病.不良反应不良反应孩子孩子孩子孩子孩子孩子基因多态化是基因的多态化.甲基甲酸二醇的使用方法甲基乙烯四基叶酸减少酶.

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