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Updated: Mar 3, 2026

Quantitative Immunofluorescence to Measure Global Localized Translation
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在细胞中通过点击释放反应激活mRNA的小分子翻译

Tess Vosman1, Friedrich Burba1, Martin Sumser1

  • 1Department of Chemistry, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.

Angewandte Chemie (International ed. in English)
|March 2, 2026
PubMed
概括

研究人员开发了一种新的mRNA帽子修饰,可以使用小分子精确控制mRNA翻译. 这一突破允许在真核细胞中按需解锁mRNA活动,从而推进mRNA疗法.

关键词:
在5′上限上然后点击化学.它们是mRNARNA.它们包括四素.翻译翻译翻译翻译翻译翻译

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