用于改善西班牙自治区内尼尔塞维马布免疫覆盖率的策略
Matilde Zornoza1, Jesús Javier Yelo Cano1, Jaime Jesús Pérez Martín1
1Prevention and Health Protection Service, Ministry of Health, Murcia, Spain.
Human vaccines & immunotherapeutics
|March 2, 2026
概括
西班牙西班牙西班牙西班牙西班牙
科学领域:
- 公共卫生 公共卫生
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
背景情况:
- 呼吸道同胞性病毒 (RSV) 在婴儿中引起严重感染.
- 尼尔塞维马布是一种长效单克隆抗体,可以预防RSV.
- 西班牙于2023年开始使用nirsevimab用于RSV预防.
研究的目的:
- 评估西班牙穆尔西亚的第二次nirsevimab免疫接种活动.
- 在婴儿中评估nirsevimab的覆盖率,及时性和公平性.
- 分析专业培训和公众信息对nirsevimab吸收的影响.
主要方法:
- 对2024年4月至2025年3月出生的婴儿进行了回顾性横截面分析.
- 评估了RSV季节期间和外出生婴儿的nirsevimab覆盖率.
- 根据出生时间和父母的出身,检查了免疫接种的及时性和公平性.
主要成果:
- 在12,606名婴儿中实现了93.5%的nirsevimab覆盖率.
- 运动期间 (96.0%) 和之前 (90.5%) 出生的婴儿的覆盖率更高.
- 外国出生的父母的子女的股权差距从5.7%降至2.3%.
结论:
- 在穆尔西亚实施Nirsevimab证明了高覆盖率,及时性和减少不平等.
- 持续的专业培训和公众信息是成功的nirsevimab计划的关键.
- 尼尔塞维马布在公共卫生计划中对RSV预防是可行的和有效的.
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