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Updated: Mar 3, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

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分子对接和动力学模拟确定了海洋海绵衍生的Halinaquinone作为一种有希望的STAT4调节器,用于风湿性心脏病

S Skariyachan1, G K Mathamangalath2, D Sebastian3

  • 1Department of Microbiology, St. Pius X College, Rajapuram, India.

SAR and QSAR in environmental research
|March 2, 2026
PubMed
概括

海洋海绵化合物Halenaquinone显示出治疗风湿性心脏病 (RHD) 的潜力. 计算研究表明,它强烈抑制STAT4,这是RHD的关键目标,提供治疗可能性.

关键词:
风湿性心脏病是一种心脏病.海洋海绵生物活性化合物 海绵生物活性化合物分子对接的分子对接.分子动力学模拟模拟药物动力学 药物动力学

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