基于Web的心血管疾病风险预测使用机器学习
Suraiya Akhter1, John H Miller2
1School of Business and Technology, Emporia State University, Emporia, KS, United States.
Frontiers in artificial intelligence
|March 2, 2026
概括
基于超图的特征评估 (HFE) 与支持矢量机 (SVM) 使用NHANES数据预测最好的心血管疾病 (CVD) 风险. 关键预测因素包括年龄,胆固醇和血压史,有助于早期检测和预防性护理.
科学领域:
- 生物医学信息学 生物医学信息学
- 医疗保健中的机器学习
- 心血管疾病研究研究
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因,需要先进的风险预测工具.
- 机器学习 (ML) 通过复杂的医疗数据分析提供了增强医疗决策的潜力.
- 有效的ML模型性能取决于输入特征的相关性和质量.
研究的目的:
- 将四种特征选择策略进行比较,以确定心血管疾病风险的最佳预测因素.
- 评估使用不同特征集开发的ML模型的预测性能.
- 提高临床应用ML模型的可解释性.
主要方法:
- 使用了国家健康和营养检查调查 (NHANES) 数据 (2021-2023).
- 比较皮尔森相关性 + 奇平方,基于ADT的评分,CVFE和HFE用于特征选择.
- 开发和评估了随机森林 (RF),SVM和XGBoost模型.
- 为了模型的可解释性,使用了夏普利添加式解释 (SHAP).
主要成果:
- 与SVM结合的HFE方法实现了最高的精度 (82.84%) 和AUC (0.9027).
- 确定了关键预测因素:年龄,总胆固醇,高血压史,胆固醇药物使用,最近使用处方药,吸烟史,收入与贫困比例,性别,教育和红细胞分布宽度.
- 开发了一个网络应用程序,用于使用HFE选择的功能预测心血管疾病风险.
结论:
- 战略特征选择显著提高了心血管疾病风险预测模型的准确性和可解释性.
- HFE方法提供了一种可靠的方法来识别关键心血管疾病风险因素.
- 这种数据驱动的策略可以帮助临床医生进行心血管风险评估和预防性护理计划.
相关概念视频
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
1.0K
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
1.0K
Assessment of the Cardiovascular System I: Subjective Data
992
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
992
Coronary Artery Disease IV: Preventive Measures
776
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
776
Sites for measuring blood pressure
3.9K
Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
The Brachial Artery: Primary Site for Blood Pressure Measurement
3.9K
Coronary Artery Disease I: Introduction
1.4K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.4K

