对患有先天性心脏病的青少年进行mHealth干预的集群随机试验: READYorNot CHD研究的理由和设计
Andrew S Mackie1,2, Adrienne H Kovacs3, Daniella San Martin-Feeney1
1Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
CJC pediatric and congenital heart disease
|March 2, 2026
概括
一个新的移动应用程序,MyREADY过渡CHD应用程序,旨在改善与先天性心脏病 (CHD) 的青少年的医疗保健过渡. 该研究将应用程序加上有限的护士教学与全面的仅护士教学进行比较.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 数字健康数字健康
- 过渡医学是过渡医学.
背景情况:
- 患有先天性心脏病 (CHD) 的青少年人数正在增加,需要有效过渡到成人医疗保健.
- 目前由护士领导的项目面临资源限制.
- 移动健康 (mHealth) 应用程序为过渡准备提供了潜在的解决方案,但缺乏结果数据.
研究的目的:
- 开发和评估MyREADY过渡性CHD应用程序,以提高青少年的CHD知识和自我管理技能.
- 评估应用程序与有限的护士教学相结合的有效性,与只有护士的全面教学相比.
主要方法:
- 一个多中心,集群随机非劣势性试验 (READYorNot CHD研究) 涉及16至17岁的中度或复杂心脏病患者.
- 参与者分为1:1的干预 (应用+有限的护士教学) 或控制 (仅护士的全面教学).
- 主要结果:过渡准备评估问卷得分的变化;次要结果:CHD知识,自我有效性,第一次成人CHD预约的时间.
主要成果:
- 这项研究正在进行中,结果正在等待.
- 半结构面试将收集有关用户体验的定性数据.
- 主要结果是从基线到18个月的过渡准备评估问卷得分的变化.
结论:
- 这些发现将为mHealth干预对于CHD过渡的临床实用性提供信息.
- 结果将指导患者,计划和决策者采用MyREADY过渡CHD应用程序.
- 这项研究解决了需要可扩展的解决方案,以改善患有心脏病的青少年的过渡结果.
相关概念视频
Randomized Experiments
9.1K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
9.1K
Study Designs in Epidemiology
1.3K
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
1.3K
Cardiomyopathy III: Hypertrophic Cardiomyopathy
578
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
578


