皮姆1通过线粒体代谢和Th17细胞分化作为炎症性关节炎的治疗标

Zepeng Su1,2, Yipeng Zeng1,2, Qibo Li1,2

  • 1Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518000, China.

PubMed
概括

莫洛尼-小鼠白血病病毒1 (Pim1) 的前病毒整合部位通过促进T助手17细胞分化驱动炎症性关节炎. 抑制Pim1,可能是通过FDA批准的尼洛丁尼,为风湿性关节炎和结性脊柱炎提供了治疗策略.

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