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Updated: Jun 21, 2026

Chromatin Interaction Analysis with Paired-End Tag Sequencing ChIA-PET for Mapping Chromatin Interactions and Understanding Transcription Regulation
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使用PNA标签对联结反应进行单多基质选

Aki Kohyama1, Sofia Barluenga1, Nicolas Winssinger1

  • 1Department of Organic Chemistry, Faculty of Sciences, University of Geneva Geneva 12004 Switzerland koyama.aki.6a@kyoto-u.ac.jp Nicolas.Winssinger@unige.ch.

Chemical science
|March 2, 2026
PubMed
概括

使用核酸 (PNA) 标记的新一多基板选 (OPMSS) 平台加速了化学结合反应的发现. 这种方法可以直接分析复杂的混合物,识别新的反应,如酸和之间的反应.

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PCR - Polymerase Chain Reaction01:32

PCR - Polymerase Chain Reaction

Overview
¹H NMR: Pople Notation01:09

¹H NMR: Pople Notation

The Pople nomenclature system classifies spin systems based on the difference between their chemical shifts. Coupled spins are denoted by capital letters with subscripts indicating the number of equivalent nuclei. When the coupled nuclei have well-separated chemical shifts, they are assigned letters that are far apart in the alphabet, such as A and X. When the difference in chemical shifts is small, coupled nuclei are named using adjacent letters of the alphabet (AB, MN, or XY).
A proton...
Tagging and Fusion Proteins01:24

Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...