马来西亚东海岸老年人医疗机构中的药物使用模式,多药和潜在的不适当药物:一个横截面研究
Azlini Ismail1, Basma Ezzat Mustafa1, Farah Natashah Mohd2
1Department of Fundamental Dental and Medical Sciences, Kulliyyah of Dentistry, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.
Journal of research in pharmacy practice
|March 2, 2026
概括
这项研究评估了马来西亚老年人的药物使用情况,发现中度多药性 (21.9%) 和低使用潜在不合适药物 (PIMs). 定期监测对于优化护理和预防这种人群中不良药物事件至关重要.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 对老年人的综合医疗需要仔细的药物管理,以防止不良药物事件.
- 多药和潜在不合适的药物 (PIMs) 是老年人群的重大问题,影响治疗结果.
研究的目的:
- 评估马来西亚的住院老年人中药物使用模式,多药房流行率和PIM使用情况.
- 应用2023年美国老年病学学会更新的酒标准®用于PIM识别.
主要方法:
- 一项涉及马来西亚养老机构73名老年人的横截面研究.
- 数据收集包括人口统计和药物使用;分析使用IBM SPSS®版本 26.
- 药物使用模式,多药和PIM被描述性地检查.
主要成果:
- 研究人口 (平均年龄72岁) 主要是马来人,男性,穆斯林,单身和卧床.
- 在21.9%的参与者中观察到多药性.
- 通常处方的药物包括脂质修饰剂和抗高血压剂. 鉴定到的PIM是普拉佐辛 (prazosin),科尔奇辛 (colchicine),洛拉泽帕姆 (lorazepam) 和普罗马辛 (chlorpromazine).
结论:
- 适度的多药房患病率凸显了在住院老年人中持续药物管理的必要性.
- 尽管PIM患病率低,但持续监测对于尽量减少药物不良反应和提高患者护理质量至关重要.
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