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Updated: Mar 3, 2026

Formation of Dispersible Taohong Siwu Tablets
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通过无溶剂scCO2加工制备费洛迪平-PEG固体分散物,并将其转化为口服可分解片

Siva S Kolipaka1, Laura A Junqueira2, Elizabeth J Pathrapankal3

  • 1Centre for Research Innovation, University of Greenwich, Medway Campus, Chatham Maritime, Chatham ME4 4TB, U.K.

ACS omega
|March 2, 2026
PubMed
概括

这项研究开发了一种绿色,无溶剂的超临界二氧化碳 (scCO) 方法,使用聚乙烯糖醇 (PEG) 制造费洛迪平 (FDP) 的固体分散 (SD). 由此产生的SDs显著改善了FDP溶解,并成功地制成口服分解片 (ODT).

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