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Updated: Mar 3, 2026

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Published on: January 3, 2018

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通过与硫法醇复合增强trimethoprim的物理化学特性

Motoki Inoue1, Masataka Ito2, Yohei Utsumi1

  • 1Department of Physical Chemistry, Hoshi University, 2-4-41 Ebara, Shinagawa 142-8501, Japan.

ACS omega
|March 2, 2026
PubMed
概括

形成trimethoprim-sulfathiazole盐复合物增强了药物的稳定性,并降低了高度性. 这种晶体修饰策略改善了BCSII类药物三甲 (TMP) 的物理化学特性.

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