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Updated: Mar 3, 2026

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用酸近距离标记用于生物对等化学的酶的定向进化

Ashley N Ogorek1, Shubhashree Pani2, Eli J Mertick-Sykes1

  • 1Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

ACS central science
|March 2, 2026
PubMed
概括

研究人员开发了一个新的生物对角保护组,并设计了酶来去除它. 该平台可用于成像,治疗和细胞信号的应用,从而实现精确的分子控制.

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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