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基因表达造型并不能预测心脏移植接受者的长期恶性瘤风险

Serkan Bektur1, Cliff Pruett2, Elena Deych2

  • 1University of Iowa, Department of Internal Medicine, Division of Cardiology, Iowa City, Iowa.

JHLT open
|March 2, 2026
PubMed
概括

心脏移植患者的AlloMap基因表达概况评分不能预测未来的恶性瘤风险. 这项研究发现,AlloMap得分与移植后新发癌症的发展之间没有显著的关联.

关键词:
基因表达特征分析心脏移植手术的心脏移植手术的心脏移植手术恶性瘤是一种恶性瘤.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
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