光污染和糖尿病风险:观察性研究的系统审查和元分析
Mengxiang Zhang1,2,3, Yafei Xie4, Dexuan Hu5
1The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Frontiers in public health
|March 2, 2026
概括
夜间过度的人工光,称为光污染,可使糖尿病风险增加31%. 室内光污染与患上糖尿病有着显著的关联,这突出了环境健康的关键问题.
科学领域:
- 环境健康 环境健康
- 代谢障碍 代谢障碍 代谢障碍
- 流行病学 流行病学
背景情况:
- 光污染,夜间过度的人工光 (LAN),是影响人类健康的新兴环境风险因素.
- 虽然已知LAN对昼夜节律的干扰,但其与糖尿病等代谢障碍的联系尚未得到充分合成.
研究的目的:
- 系统地评估和量化暴露于光污染 (室内和室外) 与糖尿病风险之间的关联.
- 综合现有关于光污染和糖尿病的观察性研究的证据.
主要方法:
- 在主要数据库 (PubMed, Web of Science, Scopus, Embase, CINAHL) 进行全面的文献搜索,并通过引用搜索进行补充.
- 六项观察性研究的系统审查和随机效应元分析,评估风险估计和异质性 (I2).
- 通过AHRQ和NOS尺度评估研究质量;通过漏斗图表和Begg测试评估出版偏差;用于证据可信度的GRADE方法.
主要成果:
- 光污染暴露与31%的糖尿病风险增加有关 (OR: 1.31,95%CI: 1.13-1.33;等级:中等).
- 发现了与严重 (OR:1.19),低至中度 (OR:1.10) 和特别是室内光污染 (OR:1.66;GRADE:所有中度) 的显著关联.
- 确定异质性的来源包括样本大小,光污染类型和研究质量.
结论:
- 光污染与糖尿病风险增加有积极的关联,室内光污染显示出特别强烈的相关性.
- 由于研究数量有限,因此需要更多的前性队列研究,以标准化的暴露评估和共同变量调整.
- 进一步的研究至关重要,以证实这些发现,并为有关光污染的公共卫生战略提供信息.
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