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Updated: Mar 3, 2026

Mapping Dysfunctional Protein-Protein Interactions in Disease
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Published on: October 24, 2025

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解开PFOS-NSCLC轴:集成网络毒理学,机器学习和因果推理确定EIF4EBP1作为一个关键的分子枢纽

Ting Huang1, Huaxin Pang2, Jundan Wang1

  • 1Department of Oncology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Zhejiang, Hangzhou, China.

Frontiers in public health
|March 2, 2026
PubMed
概括

暴露于 perfluorooctanesulfonic 酸 (PFOS) 与通过EIF4EBP1与肺癌有关,EIF4EBP1是一种影响瘤发育和免疫反应的关键基因. 这项研究揭示了EIF4EBP1作为将PFOS与肺腺癌风险连接起来的潜在桥梁.

关键词:
欧洲投资基金4EBP1门德尔的随机化负面结果的途径.网络毒理学网络毒理学非小细胞肺癌的肺癌.perfluorooctane 硫酸盐 (PFOS) 是一种含的物质.瘤免疫微环境是一个微环境.

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