高和低症状负担之间的生存时间差异,考虑到末期癌症患者的身体和情绪症状
Phitchaya Bussaba1, Non Sowanna2, Sukrit Kanchanasurakit3
1Sawanpracharak Hospital Nakonsawan Thailand Nakhon Thailand.
Journal of general and family medicine
|March 2, 2026
概括
高度的身体症状负担显著缩短了终末期癌症患者的生存期. 有效的症状管理对于优化息治疗中的剩余生存时间至关重要.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 在瘤学瘤学.
- 症状管理 症状管理
背景情况:
- 症状评估在息治疗中至关重要.
- 症状负担对末期癌症患者的生存期的独立影响尚未完全理解.
研究的目的:
- 调查埃德蒙顿症状评估系统 (ESAS) 评估的症状负担与终末期癌症患者的生存时间之间的关联.
- 为了确定身体,情绪或总症状痛苦得分是否预测生存.
主要方法:
- 一项双向观察队列研究包括143名癌症末期患者 (绩效状态≤30).
- 根据ESAS得分,患者被分为高或低症状困扰.
- 通过使用受限平均生存时间 (RMST) 和危险比率 (HR) 来分析生存率,并对共变量进行调整.
主要成果:
- 较高的身体症状负担与生存时间的显著减少有关 (在28天期间缩短了3.70天).
- 危险比率表明,随着高度的身体症状困扰 (HR=1.50),生存率下降的趋势.
- 情绪和总症状痛苦得分在调整后与生存没有显著的关联.
结论:
- 增加的身体症状负担是终末期癌症患者生存时间缩短的重要预测因素.
- 身体症状在息治疗中具有预后重要性.
- 优化症状管理,特别是身体症状,对于改善生存结果至关重要.
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